Infertility treatment has gained significant momentum in India, affecting almost 10-15% of married couples. With rising awareness and advancements in medical technology, In-Vitro Fertilization (IVF) has become a beacon of hope, with live birth success rates ranging between 15-45%.
IVF is an Assisted Reproductive Technology (ART) where an egg and sperm are fertilized under controlled conditions outside the body. The resulting embryo is transferred into the woman’s uterus for implantation.
| Patient’s Age | Success Rate |
|---|---|
| Less than 35 years | 35-45% per cycle |
| 35-40 years | 20-30% per cycle |
| Above 40 years | 5-10% per cycle |
Infertility affects nearly 10-12% of couples in India today, making the choice of a fertility clinic a life-altering decision. We urge patients to look beyond the ‘cost per cycle’ and focus on the ‘Cost per Baby’—the ultimate goal of your journey. Do not be swayed by commercial incentives or marketing gimmicks; successful IVF is built on clinical transparency, ethical practice, and individualized care, not just numbers.
01. Personalized Care: Avoid “Chain Clinics” where the main doctor is absent. Ensure your specialist personally supervises your treatment.
02. No Batching: Choose clinics that respect your body’s natural timing instead of batching patients for lab convenience.
03. Audit Results: Always ask for audited success rates. Ethical figures are transparent and age-specific.
04. Transparency: Demand a detailed discharge summary including egg quality and embryo development stages.
In Vitro Fertilization (IVF) is a highly structured medical procedure. It requires clinical precision and personalized protocols. According to Prof. (Dr.) Abha Majumdar (Advisor and emeritus consultant), Centre of IVF and Human Reproduction, Sir Ganga Ram Hospital), every couple’s IVF journey must be tailored. Therefore, we customize the process based on your specific medical background, such as PCOS, Endometriosis, or Latent Tuberculosis.
Before initiating an IVF cycle, our team conducts a thorough baseline evaluation. This assessment helps us determine the ideal treatment protocol for the couple.
During this phase, the patient receives conventional doses gonadotropin injections bases on their ovarian reserve. These hormones stimulate the ovaries to develop multiple mature egg containing follicles. Dr. Abha Majumdar emphasizes the necessity of protocol personalization according to ovarian reserve, age and underlying conditions or disease.
Clinical Insight: Standard Antagonist protocols work well for most patients. However, we adopt the old agonist protocol if we feel that should work better. However, individuals with a low ovarian reserve benefit from advanced global protocols like Duo-Stim (Dual Stimulation) This approach allows us to maximize the oocyte pool within a single menstrual cycle.
Furthermore, we meticulously monitor follicular growth through regular pelvic ultrasounds and blood tests tracking hormonal levels.
Once the leading follicles reach the optimal size (typically 17–18 mm), we administer a “Trigger Injection”. This is usually hCG and/or GnRH agonist. This shot induces final egg maturation. In addition, we precisely schedule the egg retrieval 34 to 36 hours later.
Ovum Pick-Up (OPU) is a minor, day-care surgical procedure. Our specialists perform this under total intravenous anaesthesia which does not require intubation.. As a result, the patient experiences a completely pain-free process and quick recovery with minimal side effects..
The procedure takes approximately 15–20 minutes. Therefore, the patient can safely return home the same day.
Our laboratory team fertilizes the retrieved eggs on the same day using the partner’s or a donor’s sperm. Depending on the semen parameters, we utilize one of two advanced laboratory techniques:
| Conventional IVF | ICSI (Intracytoplasmic Sperm Injection) |
|---|---|
| Embryologists place eggs and active sperm together in a petri dish. This allows fertilization to occur naturally. We prefer this for normal semen parameters. | A specialist selects a single high-quality sperm. Then, they inject it directly into the cytoplasm of a mature egg. This technique is ideal for severe male factor infertility or previous IVF fertilization failures. |
Next morning the embryologist identifies all the eggs which have been fertilized, now called embryos, separates them and allows them to grow in state-of-the-art incubators. We maintain strict physiological conditions that mimic the human body.
This is the most critical and delicate clinical step of the entire cycle. The doctor places the selected high-grade embryo directly into the uterus using an ultra-thin, flexible catheter under ultrasound guidance.
Following the embryo transfer, we prescribe hormonal medications to support the uterine lining. These include progesterone supplements via vaginal routes or injectable routes.. Finally, we schedule a definitive Beta-hCG blood test 11 to 12 days post-transfer to confirm pregnancy success.
At the Centre of IVF, we are constantly pushing boundaries. While Prof. (Dr.) Abha Majumdar’s 40+ years of expertise remains our foundation, we are moving towards integrating Artificial Intelligence (AI) to augment human clinical judgment with data-driven precision:
*We are in the process of integrating these advanced technologies to further enhance our success rates and offer patients the highest global standards of ART.*
